TY  - JOUR
A1  - Dieringer, Daniel
A1  - Schlötterer, Christian
T1  - Two Distinct Modes of Microsatellite Mutation Processes: Evidence From the Complete Genomic Sequences of Nine Species
Y1  - 2003/10/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 2242 
EP  - 2251 
DO  - 10.1101/gr.1416703 
VL  - 13 
IS  - 10 
UR  - http://genome.cshlp.org/content/13/10/2242.abstract 
N2  - We surveyed microsatellite distribution in 10 completely sequenced genomes. Using a permutation-based statistic, we assessed for all 10 genomes whether the microsatellite distribution significantly differed from expectations. Consistent with previous reports, we observed a highly significant excess of long microsatellites. Focusing on short microsatellites containing onlya few repeat units, we demonstrate that this repeat class is significantly underrepresented in most genomes. This pattern was observed across different repeat types. Computer simulations indicated that neither base substitutions nor a combination of length-dependent slippage and base substitutions could explain the observed pattern of microsatellite distribution. When we introduced one additional mutation process, a length-independent slippage (indel slippage) operating at repeats with few repetitions, our computer simulations captured the observed pattern of microsatellite distribution. 
ER  -