RT Journal
A1 Kent, W. James
A1 Haussler, David
T1 Assembly of the Working Draft of the Human Genome with GigAssembler
JF Genome Research 
JO Genome Research 
YR 2001 
FD September 01 
VO 11 
IS 9 
SP 1541 
OP 1548 
DO 10.1101/gr.183201 
UL http://genome.cshlp.org/content/11/9/1541.abstract 
AB The data for the public working draft of the human genome contains roughly 400,000 initial sequence contigs in ∼30,000 large insert clones. Many of these initial sequence contigs overlap. A program,GigAssembler, was built to merge them and to order and orient the resulting larger sequence contigs based on mRNA, paired plasmid ends, EST, BAC end pairs, and other information. This program produced the first publicly available assembly of the human genome, a working draft containing roughly 2.7 billion base pairs and covering an estimated 88% of the genome that has been used for several recent studies of the genome. Here we describe the algorithm used byGigAssembler.