TY  - JOUR
A1  - Gentles, Andrew J.
A1  - Karlin, Samuel
T1  - Genome-Scale Compositional Comparisons in Eukaryotes
Y1  - 2001/04/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 540 
EP  - 546 
DO  - 10.1101/gr.163101 
VL  - 11 
IS  - 4 
UR  - http://genome.cshlp.org/content/11/4/540.abstract 
N2  - We examined dinucleotide relative abundances and their biases in recent sequences of eukaryotic genomes and chromosomes, including human chromosomes 21 and 22, Saccharomyces cerevisiae, Arabidopsis thaliana, and Drosophila melanogaster. We found that dinucleotide relative abundances are remarkably constant across human chromosomes and within the DNA of a particular species. The dinucleotide biases differ between species, providing a genome signature that is characteristic of the bulk properties of an organism's DNA. We detail the relations between species genome signatures and suggest possible mechanisms for their origin and maintenance. 
ER  -