RT Journal
A1 Matthews, Lisa R.
A1 Vaglio, Philippe
A1 Reboul, Jérôme
A1 Ge, Hui
A1 Davis, Brian P.
A1 Garrels, James
A1 Vincent, Sylvie
A1 Vidal, Marc
T1 Identification of Potential Interaction Networks Using Sequence-Based Searches for Conserved Protein-Protein Interactions or “Interologs”
JF Genome Research 
JO Genome Research 
YR 2001 
FD December 01 
VO 11 
IS 12 
SP 2120 
OP 2126 
DO 10.1101/gr.205301 
UL http://genome.cshlp.org/content/11/12/2120.abstract 
AB Protein interaction maps have provided insight into the relationships among the predicted proteins of model organisms for which a genome sequence is available. These maps have been useful in generating potential interaction networks, which have confirmed the existence of known complexes and pathways and have suggested the existence of new complexes and or crosstalk between previously unlinked pathways. However, the generation of such maps is costly and labor intensive. Here, we investigate the extent to which a protein interaction map generated in one species can be used to predict interactions in another species.