TY  - JOUR
A1  - Breen, Matthew
A1  - Jouquand, Sophie
A1  - Renier, Corinne
A1  - Mellersh, Cathryn S.
A1  - Hitte, Christophe
A1  - Holmes, Nigel G.
A1  - Chéron, Angélique
A1  - Suter, Nicola
A1  - Vignaux, Françoise
A1  - Bristow, Anna E.
A1  - Priat, Catherine
A1  - McCann, E.
A1  - André, Catherine
A1  - Boundy, Sam
A1  - Gitsham, Paul
A1  - Thomas, Rachael
A1  - Bridge, Wendy L.
A1  - Spriggs, Helen F.
A1  - Ryder, Ed J.
A1  - Curson, Alistair
A1  - Sampson, Jeff
A1  - Ostrander, Elaine A.
A1  - Binns, Matthew M.
A1  - Galibert, Francis
T1  - Chromosome-Specific Single-Locus FISH Probes Allow Anchorage of an 1800-Marker Integrated Radiation-Hybrid/Linkage Map of the Domestic Dog Genome to All Chromosomes
Y1  - 2001/10/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 1784 
EP  - 1795 
DO  - 10.1101/gr.189401 
VL  - 11 
IS  - 10 
UR  - http://genome.cshlp.org/content/11/10/1784.abstract 
N2  - We present here the first fully integrated, comprehensive map of the canine genome, incorporating detailed cytogenetic, radiation hybrid (RH), and meiotic information. We have mapped a collection of 266 chromosome-specific cosmid clones, each containing a microsatellite marker, to all 38 canine autosomes by fluorescence in situ hybridization (FISH). A 1500-marker RH map, comprising 1078 microsatellites, 320 dog gene markers, and 102 chromosome-specific markers, has been constructed using the RHDF5000-2 whole-genome radiation hybrid panel. Meiotic linkage analysis was performed, with at least one microsatellite marker from each dog autosome on a panel of reference families, allowing one meiotic linkage group to be anchored to all 38 dog autosomes. We present a karyotype in which each chromosome is identified by one meiotic linkage group and one or more RH groups. This updated integrated map, containing a total of 1800 markers, covers >90% of the dog genome. Positional selection of anchor clones enabled us, for the first time, to orientate nearly all of the integrated groups on each chromosome and to evaluate the extent of individual chromosome coverage in the integrated genome map. Finally, the inclusion of 320 dog genes into this integrated map enhances existing comparative mapping data between human and dog, and the 1000 mapped microsatellite markers constitute an invaluable tool with which to perform genome scanning studies on pedigrees of interest. 
ER  -