TY  - JOUR
A1  - Dawson, Elisabeth
A1  - Chen, Yuan
A1  - Hunt, Sarah
A1  - Smink, Luc J.
A1  - Hunt, Adrienne
A1  - Rice, Kate
A1  - Livingston, Simon
A1  - Bumpstead, Suzannah
A1  - Bruskiewich, Richard
A1  - Sham, Pak
A1  - Ganske, Rocky
A1  - Adams, Mark
A1  - Kawasaki, Kazuhiko
A1  - Shimizu, Nobuyoshi
A1  - Minoshima, Shinsei
A1  - Roe, Bruce
A1  - Bentley, David
A1  - Dunham, Ian
T1  - A SNP Resource for Human Chromosome 22: Extracting Dense Clusters of SNPs From the Genomic Sequence
Y1  - 2001/01/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 170 
EP  - 178 
DO  - 10.1101/gr.156901 
VL  - 11 
IS  - 1 
UR  - http://genome.cshlp.org/content/11/1/170.abstract 
N2  - The recent publication of the complete sequence of human chromosome 22 provides a platform from which to investigate genomic sequence variation. We report the identification and characterization of 12,267 potential variants (SNPs and other small insertions/deletions) of human chromosome 22, discovered in the overlaps of 460 clones used for the chromosome sequencing. We found, on average, 1 potential variant every 1.07 kb and approximately 18% of the potential variants involve insertions/deletions. The SNPs have been positioned both relative to each other, and to genes, predicted genes, repeat sequences, other genetic markers, and the 2730 SNPs previously identified on the chromosome. A subset of the SNPs were verified experimentally using either PCR–RFLP or genomic Invader assays. These experiments confirmed 92% of the potential variants in a panel of 92 individuals. [Details of the SNPs and RFLP assays can be found at http://www.sanger.ac.uk and in dbSNP.] 
ER  -