RT Journal A1 Giacalone, Joseph A1 Delobette, Stephanie A1 Gibaja, Veronica A1 Ni, Lei A1 Skiadas, Yiannis A1 Qi, Rong A1 Edington, Joanne A1 Lai, Zhongwu A1 Gebauer, Damara A1 Zhao, Hongjuan A1 Anantharaman, Thomas A1 Mishra, Bhubaneswar A1 Brown, Laura G. A1 Saxena, Richa A1 Page, David C. A1 Schwartz, David C. T1 Optical Mapping of BAC Clones from the Human Y Chromosome DAZ Locus JF Genome Research JO Genome Research YR 2000 FD September 01 VO 10 IS 9 SP 1421 OP 1429 DO 10.1101/gr.112100 UL http://genome.cshlp.org/content/10/9/1421.abstract AB The accurate mapping of clones derived from genomic regions containing complex arrangements of repeated elements presents special problems for DNA sequencers. Recent advances in the automation of optical mapping have enabled us to map a set of 16 BAC clones derived from the DAZ locus of the human Y chromosome long arm, a locus in which the entire DAZ gene as well as subsections within the gene copies have been duplicated. High-resolution optical mapping employing seven enzymes places these clones into two contigs representing four distinct copies of the DAZ gene and highlights a number of differences between individual copies of DAZ.