RT Journal A1 LeBlanc, Mark D. A1 Aspeslagh, Glen A1 Buggia, Nathan P. A1 Dyer, Betsey D. T1 An Annotated Catalog of Inverted Repeats of Caenorhabditis elegans Chromosomes III and X, with Observations Concerning Odd/Even Biases and Conserved Motifs JF Genome Research JO Genome Research YR 2000 FD September 01 VO 10 IS 9 SP 1381 OP 1392 DO 10.1101/gr.122700 UL http://genome.cshlp.org/content/10/9/1381.abstract AB We have taken a computational approach to the problem of discovering and deciphering the grammar and syntax of gene regulation in eukaryotes. A logical first step is to produce an annotated catalog of all regulatory sites in a given genome. Likely candidates for such sites are direct and indirect repeats, including three subcategories of indirect repeats: inverted (palindromic), everted, and mirror-image repeats. To that end we have produced a searchable database of inverted repeats of chromosomes III and X of Caenorhabditis elegans, the first completely sequenced multicellular eukaryote. Initial results from the use of this catalog are observations concerning odd/even biases in perfect IRs. The potential usefulness of the catalog as a discovery tool for promoters was shown for some of the genes involved with G-protein functions and for heat shock protein 104 (hsp104).