TY - JOUR A1 - LeBlanc, Mark D. A1 - Aspeslagh, Glen A1 - Buggia, Nathan P. A1 - Dyer, Betsey D. T1 - An Annotated Catalog of Inverted Repeats of Caenorhabditis elegans Chromosomes III and X, with Observations Concerning Odd/Even Biases and Conserved Motifs Y1 - 2000/09/01 JF - Genome Research JO - Genome Research SP - 1381 EP - 1392 DO - 10.1101/gr.122700 VL - 10 IS - 9 UR - http://genome.cshlp.org/content/10/9/1381.abstract N2 - We have taken a computational approach to the problem of discovering and deciphering the grammar and syntax of gene regulation in eukaryotes. A logical first step is to produce an annotated catalog of all regulatory sites in a given genome. Likely candidates for such sites are direct and indirect repeats, including three subcategories of indirect repeats: inverted (palindromic), everted, and mirror-image repeats. To that end we have produced a searchable database of inverted repeats of chromosomes III and X of Caenorhabditis elegans, the first completely sequenced multicellular eukaryote. Initial results from the use of this catalog are observations concerning odd/even biases in perfect IRs. The potential usefulness of the catalog as a discovery tool for promoters was shown for some of the genes involved with G-protein functions and for heat shock protein 104 (hsp104). ER -