TY  - JOUR
A1  - Dubchak, Inna
A1  - Brudno, Michael
A1  - Loots, Gabriela G.
A1  - Pachter, Lior
A1  - Mayor, Chris
A1  - Rubin, Edward M.
A1  - Frazer, Kelly A.
T1  - Active Conservation of Noncoding Sequences Revealed by Three-Way Species Comparisons
Y1  - 2000/09/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 1304 
EP  - 1306 
DO  - 10.1101/gr.142200 
VL  - 10 
IS  - 9 
UR  - http://genome.cshlp.org/content/10/9/1304.abstract 
N2  - Human and mouse genomic sequence comparisons are being increasingly used to search for evolutionarily conserved gene regulatory elements. Large-scale human–mouse DNA comparison studies have discovered numerous conserved noncoding sequences of which only a fraction has been functionally investigated A question therefore remains as to whether most of these noncoding sequences are conserved because of functional constraints or are the result of a lack of divergence time.[The sequence data described in this paper have been submitted to the GenBank data library under accession nos. AF276990.] 
ER  -