RT Journal A1 Ohler, Uwe T1 Promoter Prediction on a Genomic Scale—The Adh Experience JF Genome Research JO Genome Research YR 2000 FD April 01 VO 10 IS 4 SP 539 OP 542 DO 10.1101/gr.10.4.539 UL http://genome.cshlp.org/content/10/4/539.abstract AB We describe our statistical system for promoter recognition in genomic DNA with which we took part in the Genome Annotation Assessment Project (GASP1). We applied two versions of the system: the first uses a region-based approach toward transcription start site identification, namely, interpolated Markov chains; the second was a hybrid approach combining regions and signals within a stochastic segment model. We compare the results of both versions with each other and examine how well the application on a genomic scale compares with the results we previously obtained on smaller data sets.