TY - JOUR A1 - Ohler, Uwe T1 - Promoter Prediction on a Genomic Scale—The Adh Experience Y1 - 2000/04/01 JF - Genome Research JO - Genome Research SP - 539 EP - 542 DO - 10.1101/gr.10.4.539 VL - 10 IS - 4 UR - http://genome.cshlp.org/content/10/4/539.abstract N2 - We describe our statistical system for promoter recognition in genomic DNA with which we took part in the Genome Annotation Assessment Project (GASP1). We applied two versions of the system: the first uses a region-based approach toward transcription start site identification, namely, interpolated Markov chains; the second was a hybrid approach combining regions and signals within a stochastic segment model. We compare the results of both versions with each other and examine how well the application on a genomic scale compares with the results we previously obtained on smaller data sets. ER -