RT Journal
A1 Mortimer, Robert K.
T1 Evolution and Variation of the Yeast (Saccharomyces) Genome
JF Genome Research 
JO Genome Research 
YR 2000 
FD April 01 
VO 10 
IS 4 
SP 403 
OP 409 
DO 10.1101/gr.10.4.403 
UL http://genome.cshlp.org/content/10/4/403.abstract 
AB In this review we describe the role of the yeastSaccharomyces in the development of human societies including the use of this organism in the making of wine, bread, beer, and distilled beverages. We also discuss the tremendous diversity of yeast found in natural (i.e., noninoculated) wine fermentations and the scientific uses of yeast over the past 60 years. In conclusion, we present ideas on the model of “genome renewal” and the use of this model to explain the mode by which yeast has evolved and how diversity can be generated.