RT Journal
A1 Boyd, Yvonne
A1 Blair, Helen J.
A1 Cunliffe, Pamela
A1 Masson, Walter K.
A1 Reed, Vivienne
T1 A Phenotype Map of the Mouse X Chromosome: Models for Human X-linked Disease
JF Genome Research 
JO Genome Research 
YR 2000 
FD March 01 
VO 10 
IS 3 
SP 277 
OP 292 
DO 10.1101/gr.10.3.277 
UL http://genome.cshlp.org/content/10/3/277.abstract 
AB The identification of many of the transcribed genes in man and mouse is being achieved by large scale sequencing of expressed sequence tags (ESTs). Attention is now being turned to elucidating gene function and many laboratories are looking to the mouse as a model system for this phase of the genome project. Mouse mutants have long been used as a means of investigating gene function and disease pathogenesis, and recently, several large mutagenesis programs have been initiated to fulfill the burgeoning demand of functional genomics research. Nevertheless, there is a substantial existing mouse mutant resource that can be used immediately. This review summarizes the available information about the loci encoding X-linked phenotypic mutants and variants, including 40 classical mutants and 40 that have arisen from gene targeting.