TY  - JOUR
A1  - Wang, Yanli
A1  - Bryant, Stephen
A1  - Tatusov, Roman
A1  - Tatusova, Tatiana
T1  - Links from Genome Proteins to Known 3-D Structures
Y1  - 2000/10/01 
JF  - Genome Research 
JO  - Genome Research 
SP  - 1643 
EP  - 1647 
DO  - 10.1101/gr.143200 
VL  - 10 
IS  - 10 
UR  - http://genome.cshlp.org/content/10/10/1643.abstract 
N2  - We describe a genome annotation service provided by the Entrez browser, http://www.ncbi.nlm.nih.gov/entrez. All protein products identified in fully sequenced microbial genomes have been compared with proteins with known 3-D structure by use of the BLAST sequence comparison algorithm. For the ∼20% of genome proteins in which unambiguous sequence similarity is detected, Entrez provides a link from the gene product to its predicted structure. The service uses the Cn3D molecular graphics viewer to present a 3-D view of the known structure, together with an alignment display mapping conserved residues from the genome protein onto the known structure. Using an example from Aeropyrum pernix, we illustrate how mapping to a 3-D structure can confirm predictions of biological function. 
ER  -