Cover image
An old man in a straw raincoat and cap represents tagging with the Fc region of rabbit immunoglobulin G. He is fishing using a rod without a hook, which represents pulling down transcription factors without using antibodies. In this issue, an antibody-free technology to profile transcription factor binding sites was developed to investigate zebrafish early embryogenesis. (Cover illustration by Yiqing Chen, evaluna.y.c{at}gmail.com. [For details, see Wang et al., pp. 378–388.])
