(A) Temporal analysis of the LGV clade indicates a most recent common ancestor (MRCA) between 200 CE and 1430 CE (95% highest posterior density [HPD]). Dates along the x-axis are in years (CE), and blue bars show the 95% posterior probability. Posterior probabilities of node positions are indicated by closed circles (P = 1) or open circles (P > 0.8). (B) The Chlamydia trachomatis LGV mutation rate is shown in the context of other viruses, bacteria and eukaryotes. Error bars differ per species according to methodology, but for the case of C. trachomatis represent 95% posterior probability. Data sources shown in Supplemental Table S3. Buchnera aphidicola, another intracellular bacterium, has a similar genome size and mutation rate.
