De novo discovery of mutated driver pathways in cancer

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Figure 5.
Figure 5.

(A) High weight submatrices of two and three genes in the glioblastoma data. (Black bars) Exclusive mutations; (gray bars) co-occurring mutations. Rows (patients) are ordered differently for each submatrix, to illustrate exclusivity and co-occurrence. (B) Location of identified genes in known pathways. Interactions in pathways are as reported in The Cancer Genome Atlas Research Network (2008).

This Article

  1. Genome Res. 22: 375-385

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