Selective sweeps and parallel mutation in the adaptive recovery from deleterious mutation in Caenorhabditis elegans

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Figure 5.
Figure 5.

Predicted interactions of recovery line and MA line mutations. Each red square represents a MA line mutation; inside the square, the genotype (MA12) is on top, the mutated gene is in the middle, and the functional effect is indicated on the bottom. UTR, mutations in untranslated regions; Ex Syn, exon mutations that are synonymous. For nonsynonymous mutations in exons, the resultant amino acid change is indicated using single-letter codes. Circles represent recovery line mutations: (green) R12A; (blue) R12C. Genetic interactions predicted by GeneOrienteer are indicated by double-headed arrows, and the log-likelihood score associated with each predicted interaction is listed next to corresponding arrows.

This Article

  1. Genome Res. 20: 1663-1671

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