
(Top) Distributions of uncorrected HS (within-population heterozygosity) for the HapMap and the Perlegen data across 5682 windows of 500 kb spanning the entire human genome. Commensurate with the upward skew to the site frequency spectrum, the HapMap data have higher heterozygosity. (Bottom) After correction for ascertainment bias, the distributions of heterozygosity are more comparable; however, the ascertainment correction appears to have inflated the variance among windows in HS.











