A Systematic Analysis of Human Disease-Associated Gene Sequences In Drosophila melanogaster

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Figure 2.
Figure 2.

Number of Drosophila sequences related to human disease genes as a function of E-value. A graph of the percent of human disease genes with similar sequences in Drosophila as a function of E-value. Black-filled bars indicate the percent of human Locuslink entries (929 total) with matches to Drosophilasequences. White-filled bars indicate the percent of uniqueDrosophila sequences that match one or more human disease gene sequences. Note that even at E-values of ≤10−40, 54% of human disease genes have matches to Drosophilasequences.

This Article

  1. Genome Res. 11: 1114-1125

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